Burroughs wrote 18 novels and novellas, six collections of short stories and four collections of essays. Five books have been published of his interviews and correspondences. Burroughs also collaborated on projects and recordings with numerous performers and musicians, and made many appearances in films.
Much of Burroughs's work is semi-autobiographical, primarily drawn from his experiences as a heroin addict, as he lived throughout Mexico City, London, Paris, Berlin, the South American Amazon and Tangier in Morocco. Finding success with his confessional first novel, Junkie (1953), Burroughs is perhaps best known for his third novel Naked Lunch (1959).