Thomas De Quincey is beginning to control his opium addiction when the excitement of his current case threatens to unravel his grip on reality once and for all. On their way home to the Lake District, the De Quinceys become unwitting witnesses to a truly historic murder: the first to take place on one of England's newly constructed railways.
The railways changed everything in the Victorian era, transforming the English countryside, revolutionizing modern industry, and as the De Quinceys discover, providing the perfect escape. Giving chase in a cat-and-mouse game unlike any that have come before, the De Quinceys uncover a dangerous secret that reaches all levels of English society.