Wanted for murder, Special FBI agent Elizabeth Keen has been framed as a KGB agent by the shadowy CABAL and has gone on the run in an attempt to find evidence that will exonerate her. However a Blacklister by the name of Ethan Donovan, aka The Arsonist, who specializes in 'disappearing' industrial-sized problems is waging a one-man war against the Cabal and literally burning their organization to the ground.