When little spider Milton discovers he has been branded deadly on social media, and is targeted by pestkillers BugKILL, he fears for his life and the future of his species. Alongside his BFFs, big hairy Ralph and spindly Daddy longlegs Audrey, he searches for a way to clear his name. But to succeed, Milton realises he must communicate with his house humans, a schoolgirl called Zoe and her arachnophobic dad. Is he mighty enough to achieve the impossible?