Nancy Skidmore has Alzheimers and her oldest friend Eugene Chaney III once more a purpose in life to end hers.
When the moment for Gene to take Nancy to her desired death in Coffeeville arrives, she is unexpectedly admitted to the secure unit of a nursing home and he calls upon his two remaining friends to help break her out: one a disgraced weatherman in the throes of a midlife crisis and the other officially dead for forty years. On a tour bus stolen from Paul McCartney, Nancy and Gene are joined by a colourful cast of characters as they career through a landscape of war, euthanasia, communism, religion and racism and along the way discover the true meaning of love, family, and, most important of all, friendship.
Charming, uplifting and profoundly moving, Last Bus to Coffeeville is a chronicle of lives that have jumped the tracks; a tale of endings and new beginnings; a funny story about sad things.