Scott Weiss is a private detective. John Foy is a professional killer known as the Shadowman. They are two sworn enemies with a single obsession: a woman on the run from them both. The woman is Julie Wyant, an ex-prostitute with a hidden past and an uncertain future. Matching each other move for move, Foy and Weiss pursue Julie from San Francisco across the badlands of Arizona to Union City, Nevada where finally they meet - on Damnation Street.